|
Integrins |
Ligands |
Other names |
|
|
b1 |
a1 |
Native collagen, laminin |
VLA1 |
|
|
a2 |
Native collagen, laminin |
VLA2 |
|
|
a3 |
Laminin, fibronectin, native collagen |
VLA3 |
|
|
a4 |
VCAM-1, fibronectin |
VLA4 |
|
|
a5 |
Fibronectin (RGD containing domain) |
VLA5 |
|
|
a6 |
Laminin |
VLA6 |
|
|
a7 |
Laminin |
|
|
|
a8 |
Fibronectin, vitronectin |
|
|
|
a9 |
Tenascin |
|
|
|
a10 |
Collagen |
|
|
|
a11 |
Collagen |
|
|
|
av |
Vitronectin, fibronectin, osteopontin |
|
|
b2 |
aL |
ICAM-1, ICAM-2, ICAM-3 |
LFA-1 |
|
|
aM |
ICAM-1, fibrinogen, C3bi, factor X |
Mac-1 |
|
|
aX |
Fibrinogen, C3bi |
P150,95 |
|
|
aD |
ICAM-3 |
|
|
b3 |
aIIb |
Fibrinogen, fibronectin, von Willebrand factor, vitronectin, thrombospondin |
|
|
|
av |
Vitronectin, fibronectin,
fibrinogen/fibrin, denaturated collagen, von Willebrand factor, thrombospondin,
fibulin, osteopontin |
|
|
b4 |
a6 |
Laminin, desmin |
|
|
b5 |
av |
Vitronectin |
|
|
b6 |
av |
Fibronectin |
|
|
b7 |
a4 |
Fibronectin, VCAM-1, MAdCAM |
|
|
|
aE |
E-cadherin |
|
|
b8 |
av |
Vitronectin |
|
Table 1. Ligand properties of Integrins (Berman et al., 2003[2])
ICAM= intercellular adhesion molecule, VCAM= vascular
cell adhesion molecule, MAdCAM=mucosal addressin cell adhesion molecule, C3b= complement 3 b, LFA=leukocyte
function associated antigen