Effects of arbutin, ursolic acid, and EGCG on expression of MMP-1 collagenase in human dermal fibroblast WS-1 cells after irradiated with UVABa

aData expressed in mean±S.D. from triplicate experiments. *p<0.01 compared with blank, #p<0.05 compared with the control.

UVAB irradiation =UVA (385nm, 1500 μw/cm2, 100 mJ/cm2) plus UVB (302nm, 1500 μw/cm2, 100mJ/cm2).

Blank: without any treatment. Concentration at 0mM: cells treated with UVAB irradiation in the absence of AB, UA and EGCG. Concentration at 1mM: cells treated with UVAB irradiation in the presence of 1mM of AB, UA and EGCG, respectively. EGCG was used as the positive control.